AC	Adenylyl cyclase
AgRP	Agouti-related peptide
CNS	Central nervous system
EC50	Half maximal effective concentration
ECL	Extracellular loop
ERK1/2	Extracellular signal-regulated protein kinases 1 and 2
GPCR	G protein-coupled receptor
Gs	Stimulatory G protein
HEK293T	Human embryonic kidney 293T
IC50	Half maximal inhibitory concentration
ICL	Intracellular loop
MAPK	Mitogen-activated protein kinase
MC3R	Melanocortin-3 receptor
MC4R	Melanocortin-4 receptor
MSH	Melanocyte-stimulating hormone
NDP-MSH	[Nle4, D-Phe7]-α-melanocyte-stimulating hormone
pERK1/2	Phosphorylated ERK1/2
PKA	Protein kinase A
TMD	Transmembrane domain