PTC	peptidyl transferase center
FDA	U.S. Food and Drug Administration
cryo-EM	cryogenic electron microscopy
NMR	nuclear magnetic resonance
rf	radiofrequency
FID	free induction decay
FT	Fourier transformation
MD	molecular dynamics
NPET	nascent peptide exit tunnel
MABP-1	macrolide antibiotic binding protein-1
SEM	scanning electron microscopy
SPA	single-particle analysis
cryo-ET	cryogenic electron tomography
ErmBL	erythromycin resistance methyltransferase B leader peptide
ErmCL	erythromycin resistance methyltransferase C leader peptide
ermaa-tRNA	erythromycin resistance methyltransferase geneaminoacyl-tRNA
p-tRNA	peptidyl-tRNA
TnaCMsrE	tryptophanase leader peptide
RSF	macrolide-streptogramin B resistance proteinribosomal silencing factor
ABC	ATP-binding cassette
NOE	nuclear Overhauser effect
STD	saturation transfer difference
trNOESY	transferred nuclear Overhauser effect spectroscopy
DOSY	diffusion-ordered NMR spectroscopy
PREs	paramagnetic relaxation enhancements
ROESY	rotating frame nuclear Overhauser effect spectroscopy
SDS	sodium dodecylsulphate
DPC	dodecylphosphocholine
BSA	bovine serum albumin
MRSA	methicillin-resistant Staphylococcus aureus
MAS	magic angle spinning
DOPC	dioleoylphosphatidylcholine
ESR	electron spin resonance
DMPC	1,2-dimyristoyl-sn-glycero-3-phosphocholine
DMPG	1,2-dimyristoyl-sn-glycero-3-phosphorylglycerol
SAR	structure-activity relationship
RDC	residual dipolar couplings
DMS	dimethyl sulfate
CMCT	1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluene sulfonate
F	fluorophore
FRET	Förster resonance energy transfer
QM	quantum mechanical
AMBER	Assisted Model Building and Energy Refinement
pBLCLZα	erythromycin-inducible ermC-β-galactosidase
CHARMM	Chemistry at HARvard Macromolecular Mechanics
PES	potential energy surface
ffTK	force field toolkit
VMD	variable molecular dynamics
GCMC	grand canonical Monte Carlo
MMFF	Merck Molecular Force Field
MOE	MOELowModeMD
MC	MacroModel