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. 2020 Oct 16;12(10):980. doi: 10.3390/pharmaceutics12100980

Table 2.

Chemical methods of extracellular vesicle (EV) surface cross-linking.

Method Binding
Triazole linkage Covalent
Disulfide linkage Covalent
Thioether bond Covalent
Amide bond Covalent
Streptovidin-Biotin interaction Non-covalent
π-π stacking interactions Non-covalent