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. 2020 Oct 13;21(20):7553. doi: 10.3390/ijms21207553

Table 1.

Equilibrium constants for hemin binding to neuronal peptides in phosphate buffer solution at pH 7.4.

Complex Log K1 Log K2 Log β2
Hemin-PrP106–114 // // //
Hemin-PrP95–114 4.80 ± 0.06 // //
Hemin-PrP84–114 6.1 ± 0.3 4.72 ± 0.07 e 10.8 ± 0.4 e
Hemin-PrP76–114 6.48 ± 0.25 // //
Hemin-Aβ16 a 4.80 ± 0.02 4.02 8.82 ± 0.02
Hemin-AcR1τ b 6.52 ± 0.02 <2 //
Hemin-Aβ42 c 6.86 6.46 13.32
Hemin-Aβ42 d 6.85 // //

Data from: a Thiabaud et al. [42], b Pirota et al. [43], c Zhou et al. [44], d Atamna et al. [45], e data estimated with two-steps low-affinity equation. // indicates a small value that could not be determined experimentally.