Table 2.
Baseline characteristics of study sample included in the continuation depression treatment phase.
| Characteristics | Adherent | Non-Adherent | Unweighted | Weighted | Unweighted | Weighted | |||
|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | χ2 | χ2 | df | p-Value | p-Value | |
| Age group | 2.298 | 0.001 | 1 | 0.130 | 0.9715 | ||||
| 65–74 years | 411 | 58.55 | 291 | 41.45 | |||||
| 75+ years | 1996 | 61.62 | 1243 | 38.38 | |||||
| Gender | 2.855 | 0.012 | 1 | 0.091 | 0.9146 | ||||
| Male | 613 | 58.89 | 428 | 41.11 | |||||
| Female | 1794 | 61.86 | 1106 | 38.14 | |||||
| Race/Ethnicity | 38.713 | 0.000 | 1 | <0.001 * | 0.9841 | ||||
| White | 2141 | 63.01 | 1257 | 36.99 | |||||
| Others | 266 | 48.99 | 277 | 51.01 | |||||
| Public Assistance | 0.416 | 0.000 | 1 | 0.519 | 0.9867 | ||||
| Yes | 1523 | 61.46 | 955 | 38.54 | |||||
| No | 884 | 60.42 | 579 | 39.58 | |||||
| Region | 15.483 | 0.007 | 3 | 0.001 * | 0.9999 | ||||
| Northeast | 507 | 63.45 | 292 | 36.55 | |||||
| South | 940 | 58.86 | 657 | 41.14 | |||||
| Midwest | 674 | 64.81 | 366 | 35.19 | |||||
| West | 286 | 56.63 | 219 | 43.37 | |||||
| Metropolitan status | 0.579 | 0.001 | 1 | 0.447 | 0.9716 | ||||
| Yes | 1850 | 60.76 | 1195 | 39.24 | |||||
| No | 557 | 62.17 | 339 | 37.83 | |||||
| Baseline PD | 1.254 | 0.000 | 1 | 0.263 | 0.9965 | ||||
| Yes | 146 | 64.60 | 80 | 35.40 | |||||
| No | 2261 | 60.86 | 1454 | 39.14 | |||||
| Provider Specialty | 19.464 | 0.059 | 4 | 0.001 * | 0.9996 | ||||
| General/Family | 1766 | 61.92 | 1086 | 38.08 | |||||
| Neurology | 37 | 44.05 | 47 | 55.95 | |||||
| Other | 284 | 55.91 | 224 | 44.09 | |||||
| Psychiatry | 132 | 62.86 | 78 | 37.14 | |||||
| Unknown | 188 | 65.51 | 99 | 34.49 | |||||
| Density of Neurologists | 4.547 | 0.038 | 3 | 0.208 | 0.9981 | ||||
| 0 | 494 | 60.76 | 319 | 39.24 | |||||
| 1 | 638 | 60.99 | 408 | 39.01 | |||||
| 2 | 617 | 58.99 | 429 | 41.01 | |||||
| 3 | 658 | 63.51 | 378 | 36.49 | |||||
| Density of Psychiatrists | 7.664 | 0.008 | 3 | 0.054 | 0.9998 | ||||
| 0 | 406 | 63.84 | 230 | 36.16 | |||||
| 1 | 654 | 59.19 | 451 | 40.81 | |||||
| 2 | 641 | 59.13 | 443 | 40.87 | |||||
| 3 | 706 | 63.26 | 410 | 36.74 | |||||
| ELX Index | 10.949 | 0.017 | 3 | 0.012 * | 0.9994 | ||||
| 0 | 441 | 59.12 | 305 | 40.88 | |||||
| 1 | 393 | 56.79 | 299 | 43.21 | |||||
| 2 | 363 | 61.01 | 232 | 38.99 | |||||
| 3 | 1210 | 63.42 | 698 | 36.58 | |||||
| Baseline medication use | |||||||||
| ACE Inhibitor | 0.232 | 0.012 | 1 | 0.630 | 0.914 | ||||
| Yes | 676 | 61.68 | 420 | 38.32 | |||||
| No | 1731 | 60.84 | 1114 | 39.16 | |||||
| Anticoagulant | 0.008 | 0.002 | 1 | 0.930 | 0.9650 | ||||
| Yes | 299 | 60.90 | 192 | 39.10 | |||||
| No | 2108 | 61.10 | 1342 | 38.90 | |||||
| Antidiabetic | 3.372 | 0.000 | 1 | 0.066 | 0.9853 | ||||
| Yes | 466 | 58.25 | 334 | 41.75 | |||||
| No | 1941 | 61.80 | 1200 | 38.20 | |||||
| Antiparkinsonian | 0.838 | 0.000 | 1 | 0.360 | 0.9879 | ||||
| Yes | 167 | 63.74 | 95 | 36.26 | |||||
| No | 2240 | 60.89 | 1439 | 39.11 | |||||
| Antipsychotic | 14.386 | 0.004 | 1 | <0.001 * | 0.9478 | ||||
| Yes | 463 | 67.49 | 223 | 32.51 | |||||
| No | 1944 | 59.72 | 1311 | 40.28 | |||||
| ARB | 0.167 | 0.008 | 1 | 0.683 | 0.9276 | ||||
| Yes | 300 | 60.24 | 198 | 39.76 | |||||
| No | 2107 | 61.20 | 1336 | 38.80 | |||||
| Anxiolytic | 6.626 | 0.036 | 1 | 0.010 * | 0.849 | ||||
| Yes | 298 | 56.02 | 234 | 43.98 | |||||
| No | 2109 | 61.87 | 1300 | 38.13 | |||||
| Betablocker | 2.952 | 0.001 | 1 | 0.086 | 0.9802 | ||||
| Yes | 992 | 62.71 | 590 | 37.29 | |||||
| No | 1415 | 59.98 | 944 | 40.02 | |||||
| CCB | 1.145 | 0.012 | 1 | 0.285 | 0.9138 | ||||
| Yes | 565 | 59.60 | 383 | 40.40 | |||||
| No | 1842 | 61.54 | 1151 | 38.46 | |||||
| Diuretic | 0.169 | 0.004 | 1 | 0.681 | 0.9504 | ||||
| Yes | 888 | 61.50 | 556 | 38.50 | |||||
| No | 1519 | 60.83 | 978 | 39.17 | |||||
| PPI | 0.301 | 0.005 | 1 | 0.583 | 0.9416 | ||||
| Yes | 729 | 61.73 | 452 | 38.27 | |||||
| No | 1678 | 60.80 | 1082 | 39.20 | |||||
| Statin | 0.264 | 0.010 | 1 | 0.607 | 0.9211 | ||||
| Yes | 925 | 61.58 | 577 | 38.42 | |||||
| No | 1482 | 60.76 | 957 | 39.24 | |||||
Note: Based on 3941 (adherent (N) = 2407 (61.08%)) older adults with dementia and newly diagnosed MDD. Abbreviations: PD: Parkinson’s disease; ELX: Elixhauser; ACE inhibitors: angiotensin-converting-enzyme (ACE) inhibitors; ARBs: angiotensin II receptor blockers; CCB: calcium-channel blockers; PPI: proton pump inhibitors. * Represents statistical significance (p-value < 0.05).