Table 6.
Selected Baseline and Final Metabolic and Hormonal Parameters | Final Insulin | ||
---|---|---|---|
Insulin 0’ (µIU/mL) | Insulin 120’ (µIU/mL) | Mean Insulin (µIU/mL) | |
Insulin 0’ at Baseline (µIU/mL) | 0.62 *** | 0.52 ** | 0.61 *** |
Insulin 120’ at Baseline (µIU/mL) | 0.46 ** | 0.60 *** | 0.38 * |
Mean insulin at Baseline (µIU/mL) | 0.62 *** | 0.62 *** | 0.74 *** |
M-clamp Value at Baseline (mg/kgffm/min) | −0.71 *** | −0.67 *** | −0.67 *** |
BMI at Follow-Up (kg/m2) | 0.83 *** | 0.52 ** | 0.73 *** |
BMI at Baseline (kg/m2) | 0.80 *** | 0.45 * | 0.66 *** |
Waist circumference at Follow-Up (cm) | 0.83 *** | 0.57 *** | 0.75 *** |
Waist circumference at Baseline (cm) | 0.87 *** | 0.60 *** | 0.74 *** |
Fat mass at Follow-Up (%) | 0.78 *** | 0.61 *** | 0.71 *** |
Fat mass at Baseline (%) | 0.74 *** | 0.51 ** | 0.66 *** |
Triglycerides at Follow-Up (mg/dL) | 0.79 *** | 0.62 *** | 0.70 *** |
Triglycerides at Baseline (mg/dL) | 0.56 ** | 0.39 * | 0.38 * |
HDL-c at Follow-Up (mg/dL) | −0.56 ** | −0.45 * | −0.52 ** |
HDL-c at Baseline (mg/dL) | −0.56 ** | −0.39 * | −0.41 * |
SHBG at Follow-Up (nmol/l) | −0.51 ** | −0.50 ** | −0.57 *** |
SHBG at Baseline (nmol/l) | −0.57 *** | −0.46 ** | −0.46 ** |
FAI at Follow-Up | 0.42 * | 0.46 ** | 0.46 ** |
FAI at Baseline | 0.32 p = 0.08 | NS | NS |
Data are shown as r correlation coefficient. Significance levels are indicated by asterisks (*, p < 0.05; **, p < 0.01; ***, p < 0.001). Correlation coefficients were estimated by Spearman’s correlation for all parameters. BMI, body mass index; FAI, free androgen index; HDL-c, high-density lipoprotein cholesterol; M-clamp value, insulin sensitivity estimated with the euglycaemic hyperinsulinaemic clamp technique; NS, non-significant; SHBG, sex hormone-binding globulin.