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In (a) the MID is larger than the MDC. In this situation, changes as large as the MID can be considered statistically significant and important to patients. In (b) the MID is smaller than the MDC. In this situation, changes as large as the MID may be important for patients, but they cannot be distinguished from measurement error [19]. Minimal detectable change (MDC). Minimal important difference (MID). Figure adapted from Terwee et al. [20].
