Figure 2.

Microbial composition in healthy individuals and patients with normal pouch function, familial adenomatous polyposis (FAP), and chronic pouchitis. The top 20 most abundant genera with phylum names, ordered from top to bottom by mean abundance, are shown for all patients and healthy individuals in (A). A principal component analysis (PCA) plot of the first two components for all samples from the patients and healthy individuals is shown in (B) and coloured accordingly. In (C) are the top 20 most influential amplicon sequencing variants (ASVs) on the first principal component (PC1) ordered from top to bottom by absolute value. Names are shown on the y-axis, with corresponding weights on the x-axis.