Table A4.
Dose–response effects of statins and omega-3 supplementation on all-cause mortality and cardiovascular death.
| All-Cause Mortality | Cardiovascular Death | ||||
|---|---|---|---|---|---|
| Intervention | RR (95% CI) | p-Value | Intervention | RR (95% CI) | p-Value |
| Atorvastatin | 0.97 (0.93–1.01) | 0.15 | Atorvastatin | 0.90 (0.83–0.98) | 0.02 |
| Pravastatin | 0.97 (0.95–1.00) | 0.05 | Pravastatin | 0.96 (0.94–0.98) | 0.001 |
| Simvastatin | 0.93 (0.80–1.07) | 0.32 | Simvastatin | 0.82 (0.74–0.91) | < 0.001 |
| Rosuvastatin | 0.91 (0.80–0.99) | 0.02 | Rosuvastatin | 0.97 (0.91–1.03) | 0.36 |
| Lovastatin | 0.93 (0.40-1.30) | 0.28 | Fluvastatin | 0.92 (0.86–0.98) | 0.01 |
| Omega-3 supplementation | 0.98 (0.95–1.01) | 0.11 | Omega-3 supplementation | 0.94 (0.89–0.99) | 0.01 |
RR, relative risk; CI, confidence interval. Data are presented as the effect of per increment in 10 mg of statins and 1000 mg of omega-3 supplementation. Bold font indicates statistical significance.