TABLE 1.

Patient characteristics

Age (y)	N = 130	Median [range]	45	[17‐91]
Blood type O a	N = 123	N [%]	56	[45.5]
FVIII at baseline – OSA	N = 130	Median [IQR]	0.10	[0.05‐0.19]*
FVIII at baseline – CSA	N = 130	Median [IQR]	0.13	[0.09‐0.22]*
Other bleeding disorders	N = 130
VWD		N [%]	4	[3.1]
Thrombocytopenia		N [%]	1	[0.8]
Unknown		N [%]	1	[0.8]
Oral anticoagulant medication	N = 130
Vitamin K antagonist		N [%]	1	[0.8]
Platelet aggregation inhibitor		N [%]	2	[1.5]
Inhibitor measurements	N = 126
Titre > 0.3 BU b		N [%]	7	[5.6]

Blood type O refers to the ABO blood type system.

Abbreviations: FVIII‐CSA, FVIII measured by the chromogenic assay; FVIII‐OSA, FVIII measured by the one‐stage assay; VWD, von Willebrand disease.

^aSeven missing.

^bPositive inhibitor measurement at time of first FVIII measurements; only measured if patient ever had a positive inhibitor test; in four patients inhibitors were never tested.

^*Significant difference, P < .001.