Table 1.
Patient characteristics and comparisons of demographics in study population according to age.
| Variable | Total Patients n = 165 |
Non-Elderly n = 93 |
Elderly n = 72 |
p Value |
|---|---|---|---|---|
| Sex (M:F) | 91:74 | 45:48 | 46: 26 | 0.058 |
| Age (y) | 62.1 ± 10.9 | 54.6 ± 7.7 | 71.8 ± 5.2 | <0.001 |
| Underlying disease | 0.028 | |||
| Lung cancer | 115 (69.7%) | 57 (61.3%) | 58 (80.6%) | |
| Breast cancer | 20 (12.1%) | 16 (17.2%) | 4 (5.6%) | |
| Other | 20 (12.1%) | 12 (12.9%) | 8 (11.1%) | |
| None | 10 (6.1%) | 8 (8.6%) | 2 (2.8%) | |
| Hypertension | 48 (29.1%) | 15 (16.1%) | 33 (45.8%) | <0.001 |
| Diabetes mellitus | 36 (21.8%) | 17 (18.3%) | 19 (26.4%) | 0.144 |
| Previous chemotherapy | 61 (37.0%) | 31 (33.3%) | 30 (41.7%) | 0.271 |
| Total Fazekas score | 2.1 ± 1.4 | 1.5 ± 0.9 | 2.9 ± 1.6 | <0.001 |
| ePVS-BG (+) | 18 (10.9%) | 3 (3.2%)18 | 15 (20.8%) | <0.001 |
| ePVS-CSO (+) | 60 (36.4%) | 21 (22.6%) | 39 (54.9%) | <0.001 |
| Intracranial volume (cm3) | 1401.1 ± 131.2 | 1402.0 ± 140.3 | 1399.9 ± 119.3 | 0.918 |
| Normalized dural lymphatic volume (mm3) | 4028.0 ± 1529.8 | 3726.5 ± 1513.9 | 4417.6 ± 1470.6 | 0.004 |
ePVS-BG=enlarged perivascular space in the basal ganglia. ePVS-CSO=enlarged perivascular space in the centrum semiovale.