Table 2.

Adverse events observed in this study.

Adverse Events	Any Grade	Grade 3/4
Liver dysfunction	21 (58.3%)	3 (8.3%)
Hypertension	16 (44.4%)	4 (11.1%)
Decreased appetite	15 (41.7%)	1 (2.8%)
Diarrhea	15 (41.7%)	3 (8.3%)
Fatigue	13 (36.1%)	1 (2.8%)
Hypothyroidism	12 (33.3%)	0 (0%)
Hands foots skin reaction	9 (25%)	1 (2.8%)
Hypoalbuminaemia	9 (25%)	1 (2.8%)
Jaundice	8 (22.2%)	2 (5.6%)
Hoarseness	7 (19.4%)	0 (0%)
Thronbocytopenia	6 (16.7%)	3 (8.3%)
Infection	5 (13.9%)	2 (5.6%)
Encephalopathy	3 (8.3%)	1 (2.8%)
Peripheral edema	3 (8.3%)	0 (0%)
Bleeding or haemorrhage	2 (5.6%)	1 (2.8%)
Proteinuria	2 (5.6%)	0 (0%)
Ascites	1 (2.8%)	0 (0%)