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. Author manuscript; available in PMC: 2021 Oct 9.
Published in final edited form as: J Biomech. 2020 Aug 28;111:110012. doi: 10.1016/j.jbiomech.2020.110012

Figure 6. LINC function is required for LIV-induced nuclear stiffening.

Figure 6.

a) Overexpressing dominant negative form of Nesprin KASH domain was used to disrupt LINC function in MSCs. b) Intact MSCs and c) isolated nuclei did not show any response to 4x LIV (N=20/grp). * p<.05, ** p<.01, *** p<.001, against control.