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Patched 1 (PTCH1) gene mutation site and domain structure of Patched 1 protein. Each color dots showed the mutations in listed Table S1. ECD1: extracellular domain 1, ECD2: extracellular domain 2, SSD: sterol sensing domain. Each dot represents one amino acid that consist PTCH1. Gray dots indicate amino acids for which no mutations have been reported.
