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. 2020 Oct 23;5(5):e000860. doi: 10.1136/esmoopen-2020-000860

Table 3.

Cox regression analyses

145 patients 157 patients
PFS OS
HR (95% CI) P value HR (95% CI) P value
Age at first ASCT 1.1 (0.93 to 1.31) 0.24 1.21 (1.02 to 1.43) 0.029
Histology
 Leiomyosarcoma (reference)
 Liposarcoma 0.86 (0.43 to 1.72) 0.67 0.75 (0.37 to 1.55) 0.44
 Synovial sarcoma 1.2 (0.63 to 2.26) 0.58 1.4 (0.72 to 2.72) 0.32
 Angiosarcoma 1.24 (0.66 to 2.32) 0.50 1.25 (0.64 to 2.47) 0.51
 Other sarcoma 1.24 (0.76 to 2.01) 0.40 1.11 (0.65 to 1.89) 0.70
Remission status prior ASCT
 CR/NED (reference)
 PR+SD 1.49 (0.92 to 2.41) 0.10 1.48 (0.87 to 2.53) 0.15
 PD 2.78 (1.62 to 4.77) 0.0002 3 (1.69 to 5.32) 0.0002
Preparative regimen
 Platinum based (reference)
 Melphalan based 0.61 (0.38 to 0.97) 0.036 0.85 (0.52 to 1.4) 0.53
 Other 0.7 (0.41 to 1.22) 0.21 1.2 (0.68 to 2.13) 0.52

Bold numbers denote statistical significance (p < 0.05).

ASCT, autologous stem cell transplantation; CR, complete remission; NED, no evidence of disease; OS, overall survival; PD, progressive disease; PFS, progression-free survival; PR, partial remission; SD, stable disease.