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. 2020 Oct 11;13(6):83. doi: 10.3892/mco.2020.2153

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Copyright: © Jia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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The differential methylation of selenoproteome between (A) normal tissues and tumors and (B) the correlation between methylation and gene expression, as well as (C) the overall survival between hypermethylation and hypomethylation. The methylation of selenoproteome and survival, as well as the correlation between methylation and gene expression, in the five leading types of cancer associated mortality were performed using GSCALite. The blue indicates the hypomethylation and the red indicates the hypermethylation in (A). Blue and red represent negative correlation and positive correlation respectively in (B). Blue indicates a higher hypermethylated survival rate and red indicates a lower hypermethylated survival rate in (C). COAD, colon adenocarcinoma; ESCA, oesophageal carcinoma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; STAD, stomach adenocarcinoma.