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. 2020 Oct 14;20(6):360. doi: 10.3892/ol.2020.12224

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Role of mast cells in regulating microenvironment immunity of gastric cancer. (A) Immunofluorescence analysis of tryptase (green) expression in a set of 40 human gastric cancer specimens and surrounding non-tumorous tissues (magnification, ×200). (B) Tryptase expression was upregulated in gastric cancer specimens. Mean intensity of Tryptase analyzed by ImageJ software fluorescence was separated into non-tumorous tissue and tumor tissue (**P<0.01 vs. non-tumorous tissue group). (C) Positive correlation between tryptase and Foxp3. Mean intensities of TGFβ1 and tryptase fluorescence were analyzed using ImageJ software. Spearman's rank correlation analysis indicated a significant positive correlation (r=0.471; P<0.05). N, non-tumorous tissue; T, tumor tissue; Foxp3, forkhead box protein 3; MCT, Mast Cell Tryptase.