Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 26;218(2):e20200487. doi: 10.1084/jem.20200487

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Kasal and Bendelac

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 1. — Generation of the novel TF reporter mice. (A) Design of CRISPR/Cas9 knock-in strategy. (B–F) Representative flow plots of ILC progenitors from a Tcf7^EGFP × Tcf7^mCherry adult BM (B), thymocytes from a Rorc^Thy1.1 adult thymus (C), mature ILCs from a Rorc^Thy1.1 SI lamina propria with Rorc-Thy1.1⁺ cells overlaid in dark gray and total ILCs in light gray (D), ILC progenitors from a Rorc^Thy1.1 x RORγt^EGFP E15 FL with RORγ(t) intracellular staining (E), and ILC progenitors from Gata3^Citrine adult BM (F). Data are representative of at least two independent experiments (B–F). DN, double negative; DP, double positive; dsDNA, double-strand DNA.