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. 2020 Oct 26;218(2):e20191054. doi: 10.1084/jem.20191054

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© 2020 Wang et al.

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Figure 7. — Adiponectin levels are down-regulated by cold stress. (A and B) The expression of adiponectin was down-regulated while expression of UCP1 was up-regulated by cold stress (6°C for 48 h) in BAT (A) and iWAT (B) of mice. n = 4/group. Data are presented as means ± SEM. *, P < 0.05; ***, P < 0.001; Student’s t test. (C and D) The circulating levels of adiponectin were decreased by acute cold stress (6°C for 48 h; C) and chronic cold stress (6°C for 6 d; D). n = 5/group. Data are presented as means ± SEM. *, P < 0.05, Student’s t test. (E and F) The mRNA levels of adiponectin were suppressed by acute cold stress (6°C for 48 h; E) and chronic cold stress (6°C for 6 d; F). n = 5/group. Data are presented as means ± SEM. *, P < 0.05, Student’s t test. ADPN, adiponectin; RT, room temperature.