H2O2 production and electron leak index during respiratory states 2, 3 and 4 measured using fluorometric detection on brain cortex samples and NADH+FADH2-linked mitochondrial respiration (with pyruvate + malate + succinate as substrates - PMS) in ovariectomized female rats treated with vehicle (Veh) or the agonist of E2 receptor α (PPT) and E2 receptor β (DPN) and exposed to room air (AIR) or chronic intermittent hypoxia (CIH). All data are box and whiskers (median, 25th and 75th percentiles, min and max values). *, † : p<0.05, and p<0.01 vs Veh AIR.