Table 4.
Differences in patient-reported outcomes (PRO) between healthy controls and arthritis patients, reported as mean values across the full 28 days of testing
| Dependant variable | Healthy controls | Arthritis patients | t test | p value |
|---|---|---|---|---|
| Paina | ||||
| In the last 24 h, reported in the evening | 0.33 (0.82) | 3.64 (2.8) | 25.56 | <0.0005 |
| During the day, reported in the evening | 0.29 (0.60) | 3.54 (2.74) | 26.20 | <0.0005 |
| Overnight, reported in the morning | 0.24 (0.68) | 3.17 (2.62) | 25.36 | <0.0005 |
| In the morning, reported upon waking | 0.32 (0.71) | 3.32 (2.65) | 26.64 | <0.0005 |
| Stiffnessb | ||||
| Duration of stiffness (maximum number of minutes) | 27.27 (42.34) | 233.68 (468.68) | 9.35 | <0.0005 |
| 30 min (% of participants) | 0.0 | 0.4 | ||
| 30 min to 1 h (% of participants) | 0.0 | 0.0 | ||
| 1–2 h (% of participants) | 21.2 | 22.6 | ||
| 2–4 h (% of participants) | 12.1 | 19.6 | ||
| 4 h (% of participants) | 0.0 | 4.5 | ||
| All day (% of participants) | 0.0 | 12.9 | ||
| None (% of participants) | 66.7 | 40.0 | ||
| Severity of stiffness during the day, reported in the evening | 0.33 (0.52) | 1.73 (0.94) | 27.56 | <0.0005 |
| Intensity of stiffness in the morning, reported upon waking | 0.41 (0.56) | 1.66 (0.56) | 25.60 | <0.0005 |
Values are given as mean (SD) unless indicated otherwise.
a
Pain was reported on a 10-point Likert scale, where 0 = no pain;
b
stiffness was rated on a scale of 0–4 with severity increasing with the score.