Table 1.

Clinicopathologic data, observed 3-year survival rate, and univariate analysis of CRC patients undergo to curative resection

Variable	n (%)	3 yrs OS (%)	Exp(B)	95% C.I.	P
Sex			0.917	0.566–1.484	0.724
Male	172 (53.3)	79.2
Female	151 (46.7)	77.6
Age			1.603	0.840–3.061	0.152
65 yr	75 (23.2)	85.9
65 yr	248 (76.8)	76.3
Type of surgery			0.491	0.272–0.884	0.018
Open	75 (23.2)	74.6
Laparoscopic	248 (76.8)	86.4
TNM staging			1.932	1.520–2.455	< 0.001
0	29 (9.0)	89.4
I	54 (16.7)	93.5
II	97 (30.0)	84.4
III	82 (25.4)	78.6
IV	61 (18.9)	51.5
pT stage			2.200	1.567–3.088	< 0.001
pT1	51 (15.7)	94.1
pT2	39 (12.0)	91.8
pT3	178 (54.9)	78.6
pT4	55 (17.0)	56.0
pN stage			1.971	1.501–2.588	< 0.001
pN0	192 (59.4)	87.0
pN1	55 (17.0)	72.2
pN2	76 (23.5)	61.7
LNR			1.932	1.485–2.513	< 0.001
LNR0	203 (62.8)	87.3
LNR1	48 (14.9)	66.3
LNR2	72 (22.3)	62.5
LODDS			2.029	1.523–2.703	< 0.001
LODDS0	165 (51.1)	88.3
LODDS1	85 (26.3)	74.8
LODDS2	73 (22.6)	61.8
Perineural invasion			6.132	2.206–17.041	0.001
Negative	316 (97.8)	79.5
Positive	7 (2.2)	26.8
Microvascular invasion			5.272	2.791–9.961	< 0.001
Negative	300 (92.9)	81.8
Positive	23 (7.1)	21.5
Radial tumor margin			0.559	0.375–0.833	0.004
1.5 cm	54 (16.7)	69.8
1.5 3.5 cm	186 (57.6)	79.5
3.5 cm	83 (25.7)	88.4
Tumor grade (G)			1.919	1.184–3.110	0.008
G1	34 (10.5)	94.1
G2	248 (76.8)	78.1
G3	41 (12.7)	65.9
P.O. complication			4.780	2.315–9.869	< 0.001
Negative	300 (92.4)	80.3
Positive	23 (7.1)	59.1
Adjuvant chemotherapy			0.413	0.245–0.697	0.001
No	159 (49.2)	86.3
Yes	164 (50.8)	70.8
Recurrance			6.959	4.278–11.318	< 0.001
No	281 (87.0)	85.8
Yes	42 (13.0)	37.7