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. 2020 Oct 27;102:310–315. doi: 10.1016/j.ijid.2020.10.060

Table 3.

Potential risk factors related to severe disease.

Severe disease N = 18 Non-severe disease N = 45 Logistic regression model(p-value)
Univariate Multivariate
Age (years)/median (IQR) 59 (52–70) 41 (35–52) <0.001 0.024
HBP 38.9% 11.1% 0.016 0.267
DM 22.2% 4.4% 0.048 0.814
Overweight 29.4% 6.7% 0.03 0.831
Cardiovascular event 27.8% 6.7% 0.034 0.932
COPD 16.7% 0% 0.999 1.000
Tobacco 83.3% 38.6% 0.013 0.785
Current 50% 25% 0.103 0.804
Past 33.3% 13.6% 0.126 0.848



CD4 < 200 cel/μL 16.7% 2.2% 0.068 0.355
Nadir CD4 < 200 cel/μL 33.3% 22.2% 0.363 0.825
PI-containing regimen 0% 13.3% 0.313 0.750
TDF-containing regimen 0% 20% 0.999 0.999
TDF or TAF-containing regimen 16.7% 28.8% 0.320 0.569

*HBP = high blood pressure; DM = diabetes mellitus; COPD = chronic obstructive pulmonary disease.