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. 2020 Oct 13;10:562074. doi: 10.3389/fonc.2020.562074

FIGURE 3.

FIGURE 3

The diagram shows how digital image analysis has highlighted the presence of weakly positive cases in the “negative” group, as assessed under a microscope. The digital evaluation is extremely sensitive and allows the pathologist to evaluate a signal positivity that is barely visible to the naked eye.