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. 2020 Oct 23;15:8201–8215. doi: 10.2147/IJN.S261671

Figure 4.

Figure 4

Cancer cell viability and uptake following treatment with CET-DOX-CMNP-TSLs. (A and B) Qualitative cellular uptake of TSLs coated with and without CET by SKBR-3 and MCF-7 cells imaged by fluorescence microscopy (scale bar = 50 µm) and the quantitative analysis of the same analyzed by flow cytometry (n=3, ***p<0.001); (C and D) Relative cell viability of SKBR-3 and MCF-7 cells incubated for 24 h with different concentrations of CMNP (as a function of Fe3O4) in CET-CMNP-TSLs with or without NIR λmax 808 nm laser irradiation (2 W/cm2 for 5 min) (n=5) (*p <0.05, **p<0.01); (E and F) Cell viability of SKBR-3 and MCF-7 cells incubated for 24 h with CET-DOX-CMNP-TSLs (as a combination function of DOX and CMNP at a ratio of 1:15) at the same concentration with and without NIR irradiation at λmax 808 nm and 2 W/cm2 for 5 min (n=5) (*p <0.05, **p <0.01,***p <0.001).