Table 1. Demographic information.
bvFTD | Healthy controls | |
---|---|---|
Number (Female) | 20 (10) | 22 (11) |
Diagnostic confidence* | 9 cases–definite+ 11 cases–probable | |
Age (std.) | 68 (9) | 65 (11) |
MMSE (std.) | 23.2 (4.9) | 29.6 (0.5) |
Interval plasma–MRI in months (std; interval range in months) | 0.2 (3.1; 0–10) | -- |
FTLD-CDR (std.) | 1.7 (0.6) | |
FTLD-CDR sum of boxes (std.) | 8.7 (4.0) | -- |
Values are given as mean and standard deviation (std).
Abbreviations: bvFTD: behavioural variant frontotemporal dementia; FTLD-CDR = frontotemporal lobar degeneration Clinical Dementia Rating; MMSE: Mini Mental State Examination.
*According to International Behavioral Variant FTD Consortium Criteria [24]. + 6 patients fulfill definite bvFTD criteria according to neuropathological examination, 2 according to genetic examination, and one according to both. Demographic factors and clinical characteristics were compared using Chi-square (x2) and Mann-Whitney U tests [Sex: x2 = 0, p > 0.9; Age: U = 155, p = 0.052; MMSE: U = 13.5, p < 0.001].