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. 2020 Oct 27;15(10):e0237548. doi: 10.1371/journal.pone.0237548

Table 5. Antibody detection by tests in COVID-19 patients (n = 97) in different time to test groups.

Tests Quantitative test value median (25%;75% percentiles)
% of positive tests in subgroup
7–14 days 15–30 days 31–57 days
n = 20 n = 35 n = 42
SNIBE 2.02 (0.23; 17.51) 4.21 (0.8; 17.94) 5.18 (1.19; 14.02)
55 69 79
Epitope 0.65 (0.3; 1.03) 0.73 (0.37; 0.96) 0.62 (0.36; 0.87)
80 89 86
Euroimmun 2.43 (0.68; 4.92)1,2 5.18 (2.32; 7.88)1 4.81 (2.40; 6.83)2
55a,b 89a 90b
Roche 3.18 (1.15; 8.24)3,4 15.05 (6.02; 51.45)3 31.90 (5.39; 43.16)4
75 83 88
Abbott 4.27 (2.23; 6.77) 6.15 (2.67; 7.76) 5.88 (3.11; 7.65)
85 86 83
DiaSorin 27 (6.46; 73.55)5,6 98.8 (28.7; 198)5 70.15 (30.2; 134)6
55c,d 86c 90d
LIPS S-RBD 3.05 (1.85; 6.08)7,8 22.69 (9.31; 59.60)7 13.48 (4.68; 34.15)8
70 91 86
LIPS N 10.49 (4.14; 35.73) 8.48 (3.38; 13.11)9 16.13 (9.12; 63.90)9
90 89 95
Biosensor NAe NAe NAe
60 69 64

Statistical difference between quantitative data

1p = 0.006

2p = 0.01

3p = 0.003

4p<0.001

5p = 0.003

6p = 0.01

7p<0.001

8p<0.001

9p = 0.005, and between percentage of positive results

ap = 0.008

bp = 0.003

cp = 0.02

dp = 0.003

eNA–not applicable. Only qualitative interpretation (absence or presence of test line).