Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 23;13:10765–10774. doi: 10.2147/OTT.S271606

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Xiao et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

(A) PCA analysis was performed and the presented variance is analyzed by PC1 and PC2; the results suggest that the two groups have significant difference and clustering effects. Heat map analysis of differential 245 miRNAs (P<0.001, average counts >5, log|FC|>1). (B). Volcano plot of differentially expressed miRNAs in patients with RCC and healthy individuals. Plotted along the x-axis is the mean of the log2 fold-change and the y-axis is the negative logarithm of the -log P‑values. Red points represent significantly upregulated miRNAs, and green points represent significantly downregulated miRNAs with a >2.0‑fold change. (C) The process of miRNA selection. Finally, we screened 22 miRNAs for further analysis. (D) Comparison of the expression of selected miRNAs in RCC and control groups.