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. 2020 Oct 23;15:2653–2662. doi: 10.2147/COPD.S270762

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© 2020 Zou et al.

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Wnt5a and Ror2 expression is induced by PM2.5 stimulation in HBECs.

Notes: (A) Western blot showed that Wnt5a production did not significantly change after 24 h of PM2.5 (5–10 g/mL) exposure, but the production were significantly increased at PM2.5 treatment of 20 μg/mL. (B) Real-time PCR results showing the dramatic upregulation of Wnt5a mRNA and Ror2 mRNA after 24 h of 20 μg/mL PM2.5 stimulation. (C) Western blot showed that Wnt5a and Ror2 protein expression did not significantly change after 3 h and 12 h of 20 μg/mL PM2.5 stimulation, but the expression were significantly increased after 24 h of 20 μg/mL PM2.5 exposure. ^#P<0.05, versus control group. n=3.

Abbreviation: PM2.5, particulate matter<2.5 μm.