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. 2020 Oct 23;15:2653–2662. doi: 10.2147/COPD.S270762

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© 2020 Zou et al.

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The NF-κB activity was regulated by Wnt5a/Ror2 signaling in PM2.5-exposed HBECs.

Notes: (A) Western blot showed that Wnt5a siRNA led to increased cytoplasmic accumulation and inhibited nuclear translocation of NF-κB in PM2.5-exposed HBECs. (B) Western blot showed that Ror2 siRNA suppressed the Ror2 protein expression in PM2.5-exposed HBECs. (C) Western blot shows that Ror2 siRNA led to increased cytoplasmic accumulation and inhibited nuclear translocation of NF-κB in PM2.5-exposed HBECs. ^#P<0.05, versus control group. *P<0.05, versus PM2.5 group, n=3.

Abbreviations: PM2.5, particulate matter<2.5μm; siRNA, small interfering RNA.