Skip to main content
. 2020 Oct 23;12:10505–10519. doi: 10.2147/CMAR.S272324

Figure 6.

Figure 6

MiR-129-5p regulated CDDP chemoresistance by targeting MMP11. (A and B) The efficiency of siRNA targeting MMP11 was examined using QRT-PCR and Western blot. HGC27/CDDP and AGS/CDDP cells were then transfected with anti-miR-129-5p, anti-NC, anti-miR-129-5p+si-MMP11 or anti-miR-129-5p+si-NC. (C and D) The expression of MMP11 in these cells was detected by qRT-PCR and Western blot. In these indicated cells, (E) cell proliferation, (F) colony formation, (G) cell apoptosis, (H) cell migration, (I) cell invasion and (J) cell adhesion were assessed by CCK-8 assay, colony formation assay, flow cytometry assay, scratch assay, transwell assay and cell adhesion assay, respectively. (K) The expression of fibronectin and vitronectin was quantified by Western blot. *P<0.05, **P<0.01, ***P<0.001.