Table 5.
Association of TG/HDL-C Ratio with Myocardial Injury, Heart Failure, Severity, and Mortality in All Patients with COVID-19
| TG/HDL-C | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| Myocardial injury | ||||||
| T1 | 1.00 | 0.016 | 1.00 | 0.009 | 1.00 | 0.069 |
| T2 | 4.33 (1.24–15.21) | 0.022 | 4.56 (1.20–17.35) | 0.026 | 4.83 (0.57–40.75) | 0.147 |
| T3 | 6.18 (1.76–21.71) | 0.005 | 8.71 (2.18–34.74) | 0.002 | 20.72 (1.57–272.99) | 0.021 |
| Per unit increase | 1.40 (1.07–1.84) | 0.014 | 1.61 (1.17–2.23) | 0.004 | 4.52 (1.27–16.18) | 0.020 |
| Heart failure | ||||||
| T1 | 1.00 | 0.001 | 1.00 | 0.001 | 1.00 | 0.026* |
| T2 | 3.57 (1.22–10.46) | 0.020 | 3.78 (1.20–11.89) | 0.023 | 5.01 (0.91–27.54) | 0.064* |
| T3 | 7.86 (2.56–24.15) | 0.000 | 11.47 (3.26–40.40) | 0.000 | 13.38 (1.97–91.07) | 0.008* |
| Per unit increase | 1.85 (1.27–2.71) | 0.002 | 2.04 (1.36–3.06) | 0.001 | 2.64 (1.17–5.94) | 0.019* |
| Severity | ||||||
| T1 | 1.00 | 0.048 | 1.00 | 0.036 | 1.00 | 0.050 |
| T2 | 1.88 (0.70–5.01) | 0.210 | 1.77 (0.64–4.86) | 0.271 | 1.32 (0.27–6.42) | 0.732 |
| T3 | 3.67 (1.30–10.32) | 0.014 | 4.13 (1.40–12.18) | 0.010 | 20.71 (1.69–279.63) | 0.018 |
| Per unit increase | 1.51 (1.09–2.01) | 0.014 | 1.57 (1.13–2.19) | 0.008 | 3.01 (1.08–8.38) | 0.035 |
| Mortality | ||||||
| T1 | 1.00 | 0.006 | 1.00 | 0.002 | 1.00 | 0.036 |
| T2 | 3.43 (1.03–10.86) | 0.045 | 3.54 (1.01–12.55) | 0.050 | 2.12 (0.35–12.87) | 0.412 |
| T3 | 6.94 (2.13–22.65) | 0.001 | 10.87 (2.84–41.56) | 0.000 | 14.81 (1.82–120.36) | 0.012 |
| Per unit increase | 1.45 (1.10–1.93) | 0.009 | 1.65 (1.20–2.28) | 0.002 | 2.94 (1.22–7.12) | 0.017 |
Notes: Model 1: unadjusted; Model 2: adjusted for age and gender; Model 3: adjusted for age, gender, lymphocyte count, HbA1C, hs-CRP, NT-proBNP, and creatinine. *Odds ratio for heart failure was adjusted for age, gender, lymphocyte count, HbA1C, hs-CRP, and creatinine.
Abbreviations: TG/HDL-C, triglyceride/high-density lipoprotein cholesterol; COVID-19, coronavirus disease 2019; OR, odds ratio; CI, confidence interval; T, tertile.