TABLE 3.

Fetal cardiac functional parameters and cardiac outputs

Parameter	Control (n=7)	IAI (n=15)	IAI+AZI (n=8)	P value
Tricuspid E:A ratio	0.74±0.09	0.80±0.11	0.74±0.16	.577
Mitral valve E:A ratio	0.73±0.08	0.68±0.09#	0.81 ±0.10	.045
Left ventricular TEI	0.47±0.04	0.45±0.08	0.40±0.07	.235
Right SF (%)	29.22±4.22	38.05±10.51	33.34±5.76	.077
Left SF (%)	29.95±3.18	34.98±9.79	32.89±10.67	.079
Right SF/left SF	1.77±1.15	1.16±0.44	1.11 ±0.44	.987
RCO (mL/min)	92.61 ±27.60	100.04±15.82	109.86±26.76	.989
LCO (mL/min)	93.48±18.03	61.93±12.36*,#	72.98±8.29	<.001
CCO (mL/min)	189.14±62.67	162.52±24.73	169.92±31.89	.369
RCO:LCO	1.33±0.21	1.60±0.33	1.38±0.21	.092
Abnormal RCO:LCO (>1.6)	0.0%	53.3%*,#	27.6%	.022

P<.05 was considered significant by one-way analysis of variance. Symbols indicate significant differences between groups by post hoc analysis:

^*Control vs IAI;

^#IAI vs IAI+AZI. Data are expressed as mean±SD or %.

AZI, azithromycin treatment group; CCO, combined cardiac output; E:A ratio, ratio of peak velocity of early diastolic transmitral flow to the peak velocity of late diastolic transmitral flow; IAI, intraamniotic infection; LCO, left cardiac output; RCO, right cardiac output; SF, shortening fraction; TEI, isovolumic contraction time plus isovolumic relaxation time divided by ejection time.