. 2020 Oct 6;22(10):701–708. doi: 10.1089/dia.2019.0416

Table 1.

Features of the Main Glycemic Variability Calculation Tools That Are Available in Literature

Glycemic variability calculation tools	Features
Glycemic variability calculation tools	Metrics available	Environment	Open source
EasyGV	Mean, standard deviation, CONGA, Lability Index, J-index, LBGI, HBGI, GRADE, %GRADE-hypo, %GRADE-hyper, %GRADE-Eu, MODD, MAGE, ADRR, M-value, and MAG.	User-friendly software application developed in visual basic and enabled in an Excel (Microsoft).	Yes
EasyGV	Times in ranges, PGS, IGC, GVP, have been included in the last version (EasyGV v10).		Yes
GlyCulator¹⁹	Standard deviation, %CV, MAGE, weighted average of glucose values, J-index, MODD, CONGA, fractal dimension.	There are two available versions: Web-based application and installable application.	Yes
The MAGE computer program²⁰	MAGE	Software program	Yes
GVAP²¹	Average area above/below target range, percentage spent above/below target range, CONGA, MODD, MAGE, excursion frequency, MAGE.	Software application developed with MATLAB	Yes
CGManalysis²²	Sensor use, eA1c, GMI, median, quartiles, SD, CV, minimum/maximum, excursions above and below threshold, times in ranges, area under curve, MAGE, J-index, CONGAn, MODD, LBGI, HBGI.	Implemented in R	Yes

ADRR, average daily risk range; CGM, continuous glucose monitoring; CONGA, continuous overlapping net glycemic action; CV, coefficient of variation; GIC, Index Glucose Control; GMI, Glucose Management Indicator; GRADE, Glycemic Risk Assessment in Diabetes Equation; GVAP, Glycemic Variability Analyzer Program; GVP, glycemic variability percentage; HBGI, high blood glucose index; LBGI, low blood glucose index; MAG, mean absolute glucose; MAGE, mean amplitude of glycemic excursions; MODD, mean of daily differences; PGS, personal glycemic state.