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Effects of EGF on the sensitivity of ALK and RET translocated cells to ALK and RET TKIs. The TKI's were added at the final concentrations indicated and EGF or TGFα at 10 ng/mL. Medium was RPMI+0.5% HS in all cases. (A-I) Results of 72 h proliferation assays. Data were pooled from at least three different experiments and presented as mean ± SEM. *, P < 0.05 compared to EGF treated cells.
