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. 2020 Jul 16;57(12):1445–1451. doi: 10.1007/s00592-020-01567-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Orosensory and microbiome analysis of diabetic high-lipid tasters (DHLT) and diabetic low-lipid tasters (DLLT). Panel a Orosensory perception threshold of linoleic acid (LA). b Distribution of the most abundant resolved taxa at the genus level. c Microbiota alpha diversity. d Cladogram analysis of 16S sequences from circumvallate papillae and histogram showing the taxonomic groups (P < 0.05; LDA score 2.0). e Linear regression analyses between the frequency of identified bacterial taxa and perception threshold of LA. f Cladogram derived from KEGG pathway contributions of predicted metagenomic data. The relative predicted gene count histogram shows the KEGG pathway modules (P < 0.05; LDA score 2.0). Means ± SEM, P < 0.001. M metformin, S statins (color figure online)