Table 6.
Quality of Life, EORTC-QLQ C30, Brief Illness Perception Questionnaire (BIPQ), Distress thermometer and HADS, Self-efficacy, Perceived Efficacy in Patient-Physician Interactions (PEPPI), The Medical Care Questionnaire-Communication subscale (MCQ-C), mean scores (SD)
| Baseline | During treatment | Follow-up | Between group differences* | ||||
|---|---|---|---|---|---|---|---|
| Intervention | Control | Intervention | Control | Intervention | Control | ||
| QoL | |||||||
| Functional measures | |||||||
| Physical | 85.9 (12.6) | 85.7 (14.6) | 77.4 (16.4) | 81.1 (16.3) | 76.6 (16.4) | 79.1 (16.0) | n.s |
| Role | 66.7 (28.1) | 68.6 (29.8) | 58.5 (25.3) | 64.4 (30.9) | 57.2 (26.3) | 66.3 (25.6) | n.s |
| Emotional | 79.6 (17.9) | 74.4 (17.6) | 74.2 (19.8) | 75.7 (19.0) | 75.2 (20.8) | 76.0 (22.6) | n.s |
| Social | 74.8 (22.9) | 76.9 (25.0) | 72.1 (22.8) | 71.1 (27.6) | 73.5 (20.1) | 72.9 (19.9) | n.s |
| Cognitive | 78.3 (23.1) | 77.0 (22.1) | 76.5 (21.5) | 76.3 (23.4) | 72.7 (21.0) | 72.1 (22.6) | n.s |
| Global health | 69.7 (17.4) | 68.6 (21.7) | 62.7 (19.8) | 60.7 (21.6) | 61.9 (19.0) | 63.6 (17.5) | n.s |
| Symptoms | |||||||
| Fatigue | 40.7 (24.1) | 40.0 (24.2) | 47.2 (21.5) | 44.7 (24.9) | 43.2 (22.6) | 40.8 (26.8) | n.s |
| Pain | 16.3 (20.7) | 16.3 (24.4) | 23.6 (31.8) | 17.4 (24.1) | 25.0 (28.4) | 22.5 (20.9) | n.s |
| Nausea | 15.7 (26.5) | 15.4 (23.8) | 9.8 (18.2) | 10.7 (14.7) | 6.8 (15.4) | 3.5 (7.8) | n.s |
| Appetite loss | 20.9 (27.5) | 23.7 (30.5) | 17.9 (27.0) | 24.2 (23.1) | 9.1 (18.1) | 11.6 (17.6) | n.s. |
| Constipation | 29.4 (33.8) | 19.9 (29.7) | 19.5 (27.9) | 17.8 (22.0) | 15.9 (26.4) | 14.7 (22.2) | n.s |
| Diarrhea | 15.0 (32.2) | 23.1 (32.7) | 17.9 (24.8) | 8.3 (21.7) | 10.6 (21.3) | 13.2 (27.4) | n.s |
| Insomnia | 34.0 (32.3) | 32.7 (31.3) | 36.6 (33.2) | 31.1 (31.7) | 31.8 (24.9) | 34.9 (34.8) | n.s |
| Dyspnea | 14.4 (23.3) | 12.8 (20.0) | 30.0 (28.0) | 23.0 (23.4) | 24.2 (31.6) | 24.8 (25.3) | n.s |
| Financial impact | 11.1 (25.5) | 15.4 (27.6) | 10.0 (20.3) | 13.3 (24.0) | 13.6 (24.2) | 15.5 (30.3) | n.s |
| BIPQ | |||||||
| Consequences | 7.4 (1.9) | 6.7 (2.2) | 6.8 (2.2) | 6.7 (2.5) | 6.5 (2.3) | 6.7 (2.1) | n.s |
| Timeline | 5.4 (2.8) | 5.9 (3.2) | 5.5 (2.8) | 5.7 (2.6) | 6.1 (3.1) | 5.6 (3.0) | n.s |
| Personal control | 4.7 (3.1) | 4.7 (2.6) | 4.6 (2.7) | 3.8 (2.9) | 4.7 (2.9) | 4.0 (2.6) | n.s |
| Treatment control | 8.8 (1.0) | 8.5 (1.5) | 8.6 (1.4) | 8.0 (1.8) | 8.4 (1.7) | 8.3 (1.5) | n.s |
| Identity | 4.2 (2.2) | 3.3 (2.2) | 5.2 (2.2) | 4.1 (2.6) | 5.4 (2.2) | 5.2 (2.4) | n.s |
| Concern | 5.5 (2.6) | 6.2 (2.7) | 5.0 (2.3) | 5.8 (2.7) | 5.3 (2.4) | 6.0 (2.5) | n.s |
| Understanding | 6.8 (2.3) | 6.8 (2.6) | 6.8 (2.0) | 6.9 (2.0) | 7.0 (2.4) | 6.8 (2.2) | n.s |
| Emotional response | 4.8 (2.5) | 5.2 (2.5) | 4.3 (2.5) | 5.3 (2.7) | 5.3 (2.3) | 5.5 (2.5) | n.s |
| Distress thermometer | |||||||
| HADS | 4.3 (2.2) | 3.7 (2.3) | 4.9 (2.1) | 4.0 (2.5) | 4.2 (2.0) | 4.7 (2.3) | n. s |
| Anxiety | 10.4 (1.4) | 9.9 (1.8) | 10.6 (2.0) | 10.2 (1.5) | 10.4 (1.5) | 10.1 (1.9) | n.s |
| Depression | 10.8 (1.3) | 10.7 (1.9) | 10.5 (1.8) | 10.6 (1.5) | 10.6 (1.5) | 10.8 (1.5) | n.s |
| PEPPI | 44.4 (5.2) | 42.5 (5.8) | 42.8 (9.7) | 43.8 (6.7) | 45.5 (4.3) | 43.6 (5.5) | n.s |
| MCQ-C | 70.1 (21.2) | 64.0 (18.6) | 72.6 (18.4) | 64.1 (20.3) | 74.8 (18.6) | 65.0 (18.3) | n.s |
*Mixed model analysis