Table 5.
Results from Multivariate Cox models: Hazard ratios with 95% Confidence intervals assessing the association with time to local relapse (LR).
| Variables | Contrasts | Hazard ratio | Low .95 CI | Up .95 CI | P-value |
|---|---|---|---|---|---|
| I model | |||||
| FCGR1A | High vs low | 0.21 | 0.08 | 0.56 | 0.001 |
| FCRLA | High vs low | 0.34 | 0.13 | 0.89 | 0.02 |
| IFNA17 | Positive vs null | 0.06 | 0.009 | 0.53 | 0.01 |
| II model | |||||
| FCGR1A | High vs low | 0.30 | 0.10 | 0.90 | 0.03 |
| FCRLA | High vs low | 0.32 | 0.12 | 0.85 | 0.02 |
| IFNA17 | Positive vs null | 0.09 | 0.01 | 0.74 | 0.02 |
| TILs stromal | ≥ 5% vs < 5% | 0.06 | 0.12 | 0.38 | 0.002 |
Cut-off identified considering quantiles of log gene expression; High (n = 33) means greater than first quartile (n = 11), for IFNA17 the first quartile is zero; TILs: n = 37 with ≥ 5 and n = 6 with < 5.