Table 6.
Results of multivariate logistic models: Odd ratios assess the association of gene expression with pN status and pT status.
| Endpoint | Variable | Contrasts | Odd Ratio | Low.95 CI | Up.95 CI | P-value |
|---|---|---|---|---|---|---|
| pN: pN + vs pN0 | KREMEN1 | High vs low | 10.98 | 1.66 | 72.57 | 0.01 |
| CD14 | High vs low | 0.07 | 0.009 | 0.55 | 0.01 | |
| NCR3 | High vs low | 26.15 | 2.21 | 308.73 | 0.009 | |
| pT: pT4 vs pT1-3 | IFITM2 | High vs low | 7.1 | 1.21 | 41.56 | 0.02 |
| CD79A | High vs low | 0.26 | 0.06 | 1.02 | 0.05 |
KREMEN1 (Kringle Containing Transmembrane Protein 1); CD14 (CD14 Molecule); NCR3 (Natural Cytotoxicity Triggering Receptor 3); IFITM2 (Interferon Induced Transmembrane Protein 2); CD79A (CD79a Molecule); Q: quartile; Cut-off refers to quantiles of log gene expression. For Kremen1, CD14 and CD79A ‘high’ refers to greater than median value, for NCR3 ‘high’ refers to greater than first quartile (n = 11) and for IFITM2 greater than third quartile (n = 11).