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. 2020 Oct 27;3:140. doi: 10.1038/s41746-020-00351-x

Table 1.

Prospective studies examining mobile sensor data and clinical outcomes in oncology patients.

Author and yearref Number of patients Mean/median age Type of patients Device(s) used Timing Outcome
Bennett et al.24 32 55 Hematopoietic stem cell transplant Fitbit Flex During transplant hospitalization and 4 weeks post-discharge PRO-CTCAE for toxicities and symptoms and PROMIS physical health, mental health, and quality of life
Bade et al.25 39 66 Advanced lung cancer Fitbit Zip For 7 days at varying points in treatment EORTC QLQ-30 quality of life, PHQ-9 depressive symptoms, MMRC dyspnea scale
Gupta et al.26 24 54 Mixed cancer Fitbit Flex 12 weeks during systemic therapy ECOG Performance Status, FACT-G quality of life, QIDS-SR16 depressive symptoms, BFI fatigue
Ohri et al.27 50 66 Locally advanced non-small cell lung cancer Garmin Vivofit Before start of chemoradiation therapy to completion of the first week (median 17 days) Hospitalization during radiation, completion of radiation without delay, progression-free and overall survival
Ohri et al.28 38 64 Head and neck, lung, and gastrointestinal cancer Garmin During concurrent chemoradiotherapy Unplanned hospitalization during treatment
Low et al.29 71 57 Metastatic peritoneal cancer Fitbit Flex or Charge During inpatient recovery from cytoreductive surgery with hyperthermic intraperitoneal chemotherapy 30- and 60-day readmission
Sun et al.30 20 56 Hepatobiliary and gastrointestinal cancer Garmin Vivovit 2 3–7 days before surgery, during inpatient recovery, and up to two weeks following discharge 30-day comprehensive complication Index based on Clavien-Dindo classification
Gresham et al.31 37 62 Mixed advanced cancer Fitbit Charge HR 14 days during or awaiting chemotherapy or radiation therapy Provider-assessed ECOG & Karnofsky performance status, adverse events, hospitalizations, 6-month survival
Soto-Perez-de-Delis et al.42 40 73 Mixed solid tumors Android smartphone with Google Fit pedometer app Before (median 11 days) and during (median 21 days) chemotherapy Grade 2 or 3 toxicities (commonly fatigue, nausea/vomiting, diarrhea, infections)
Panda et al.43 62 66 Mixed cancer iOS or Android smartphone with Beiwe sensing app Before (median 5 days) and after (median 147 days) cancer surgery Clinically significant postoperative events
Low et al.44 14 60 Gastrointestinal cancer Android smartphone with AWARE sensing app and Fitbit charge HR Four weeks during chemotherapy Daily symptom burden
Cai et al.45 7 60 Breast cancer iOS or Android smartphone with Sensus sensing app Seven weeks during active treatment Daily and weekly mood, anxiety, and depression ratings
Wright et al.46 10 60 Gynecologic cancer iOS or Android smartphone with Beiwe sensing app, Fitbit Zip and Charge 2 30 days during chemotherapy Daily PRO-CTCAE toxicities and PROMIS quality of life
Pavic et al.47 30 64 Metastatic cancer Everion bracelet by Biovotion plus Samsung Galaxy S5 12 weeks starting at discharge from the hospital Emergency visits, readmissions, and deaths