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. 2020 Oct 27;10:18358. doi: 10.1038/s41598-020-74655-z

Table 6.

Association between the presence of each opportunistic pathogen evaluated in this study on vaginal infection.

Opportunistic pathogen P-value OR 95% CI Adjusted P-value
Atopobium vaginae 0.003** 2.03 1.28–3.23 0.006**
Mobiluncus mulieris 0.000*** 20.76 4.51–95.45 0.000***
Gardnerella spp. 0.000*** 2.34 1.47–3.73 0.000***
Escherichia coli 0.027* 2.03 1.08–3.79 0.041*
Enterococcus faecalis 0.722 1.35 0.26–7.08 0.722
Candida albicans 0.047* 4.63 1.02–21.06 0.056

Univariable logistic regression analyses were conducted to examine how different opportunistic pathogens (independent variables) were associated with the presence of vaginal infection (dependent variable). The absence of each pathogen was used as reference for this statistical analysis. Odds ratios (OR) and 95% confidence intervals (CI) obtained as measurements of relative risks and the assessments of independent risk factors for vaginal infection establishment. A value of P < 0.05 and 95% confidence intervals were considered significant for the test: *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001. All initial values of P < 0.05 obtained by univariable logistic regression analyses were then evaluated through Benjamini–Hochberg (BH) adjustment to detect false discovery rate (FDR) for conducting multiple comparisons. These P-values evaluated by BH adjustment were illustrated in the table as adjusted P-values.