Table 1.
The list of differentially expressed proteins in the anterior insula that overlap between morphine vs. saline and morphine-DBS vs. morphine and morphine-DBS vs. saline comparison.
| Protein ID | Protein name | Morphine vs. Saline | Morphine-DBS vs. Morphine | Morphine-DBS vs. Saline | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Down/Up | Fold Change | P-value | Down/Up | Fold Change | P-value | Down/Up | Fold Change | P-value | ||
| A0A0G2K526 | Guanine nucleotide-binding protein G(olf) subunit alpha | Down | 0.7648 | 0.0294 | Up | 1.7456 | 0.0217 | |||
| A0A0G2K933 | Eukaryotic translation initiation factor 4E family member 2 | Up | 1.2197 | 0.0267 | Down | 0.7490 | 0.0007 | |||
| B2RYT9 | Translational activator of cytochrome c oxidase 1 | Down | 0.7964 | 0.0443 | Up | 1.9842 | 0.0012 | Up | 1.5803 | 0.0020 |
| A0A140TAH3 | Glutamate-rich WD repeat-containing protein 1 | Down | 0.7002 | 0.0391 | Up | 1.7305 | 0.0461 | |||
| O88658 | Kinesin-like protein KIF1B | Down | 0.7763 | 0.0125 | Up | 1.6088 | 0.0001 | Up | 1.2489 | 0.0049 |
| Q64350 | Translation initiation factor eIF-2B subunit epsilon | Down | 0.5732 | 0.0127 | Up | 1.6132 | 0.0026 | |||
| Q8R462 | Amino acid transporter | Up | 1.3149 | 0.0213 | Down | 0.5170 | 0.0008 | Down | 0.6797 | 0.0338 |
| Q9WTT7 | Basic leucine zipper and W2 domain-containing protein 2 | Down | 0.8280 | 0.0028 | Up | 1.3536 | 0.0015 | |||