TABLE 2.
Transcriptomic profiling of yeast to elucidate cellular responses to phenolic inhibitors.
| Screening tool | Fermentation inhibitor | Significant biological processes | References |
| Microarray analysis of a tolerant strain (non-stressed conditions) | Vanillin | Ergosterol biosynthesis Mitochondrial function | Endo et al., 2009 |
| Microarray analysis of a tolerant strain (non-stressed conditions) | Coniferyl aldehyde | Oxido-reductase activity Oxidative stress response | Hacısalihoǧlu et al., 2019 |
| Microarray analysis of a tolerant strain (non-stressed conditions) | Vanillin | Oxido-reductase activity Oxidative stress response | Shen et al., 2014 |
| Microarray analysis of a tolerant strain (non-stressed conditions) | Vanillin | Response to stress Phospholipid metabolism | Wang X. et al., 2017 |
| Microarray analysis of evolved strain (stressed conditions) | Softwood hydrolysate | Oxidative stress response Membrane transport | Thompson et al., 2016 |
| Microarray analysis of wild type strain (stressed conditions) | Vanillin | TCA cycle Aerobic respiration | Park and Kim, 2014 |
| Microarray analysis of wild type strain (stressed conditions) | Coniferyl aldehyde | Oxido-reductase activity Mitochondrial function | Sundström et al., 2010 |
| Microarray analysis of wild type strain (stressed conditions) | Ferulic acid | Protein import Mitochondrial function | Sundström et al., 2010 |
| Microarray analysis of wild type strain (stressed conditions) | Isoeugenol | Mitochondrial function | Sundström et al., 2010 |
| Microarray analysis of yrr1Δ strain (stressed conditions) | Vanillin | Ribosome biogenesis rRNA processing | Wang X. et al., 2017 |