FIGURE 4.

Additive potentiation of GABA-induced [³H]EBOB displacement in rat forebrain with humulone combined with 6PN and IXN at 1 μM. Control is the maximal [³H]EBOB binding in the presence of 3 μM GABA alone. Each vertical bar represents the mean ± SEM, n = 3, measured in triplicates.^###p < 0.001, ^##p < 0.01 for the significance of difference from the corresponding individual compounds, **p < 0.01 for the significance of difference between 6PN+IXN+Hum and 6PN+IXN (One-way ANOVA followed by Tukey’s post hoc test).