TABLE 1.

Effects of GABA on [³H]EBOB binding in rat forebrain and cerebellar membranes with humulone in the presence or absence of ethanol (EtOH).

Membrane	IC50 (μM)
	GABA	GABA + 1 μM Humulone	GABA + 1 μM Humulone + 30 mM EtOH
Forebrain	6.73 ± 0.18	5.48 ± 0.09**	4.60 ± 0.08
Cerebellum	2.89 ± 0.09	2.40 ± 0.06**	1.80 ± 0.07

The IC₅₀ values represent mean ± SEM (n = 3, measured in triplicates). **p < 0.01, significantly different from the corresponding IC₅₀ of GABA alone and GABA+Humulone+EtOH (One-way ANOVA followed by Tukey’s post hoc test).