Table 1.

FPS-ZM1 lead profiling screen assay results. Primary assays were performed at 10 μM FPS-ZM1 to determine the percent inhibition.

Assay name	%Inhibition at 10 μM
Androgen receptor	88
Peripheral benzodiazepine receptor	85
Kappa opioid receptor	82
Adenosine A3 receptor	64
Cl-channel (GABA-gated)	62
Central benzodiazepine receptor	59
MT1 (h)a	54
MT2 (h)b	54

^aMT₁ (K_i = 1.2 μM, IC₅₀ = 1.5 μM).

^bMT₂ (K_i = 4.4 μM, IC₅₀ = 7.0 μM).