Table 3.
DNA binding constants of some drugs at room temperature.
| Drug | DNA binding constant (M−1) | Proposed binding mode | Reference |
|---|---|---|---|
| Lamivudine | 1.3 × 105 | Groove binding | [32] |
| Ribavirin | 4.3 × 103 | Groove binding | [33] |
| Oseltamivir | 1.8 × 104 | Intercalation | [34] |
| Daunomycin | 7.0 × 105 | Intercalation | [20] |
| Netropsin | 2.8 × 108 | Groove binding | [21] |
| Diminazene | 8.8 × 108 | Groove binding | [22] |
| Gemcitabine | 2.0 × 106 | Groove binding | [23] |
| Indinavir | 1.6 × 108 | Groove binding | This study |