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. 2020 Oct 14;11:551256. doi: 10.3389/fmicb.2020.551256

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Copyright © 2020 Oliveira, Medina-Alarcón, Singulani, Fregonezi, Pires, Arthur, Fusco-Almeida and Mendes Giannini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantitative analysis of biofilm formation in vitro by CFU/mL (Log10) count for the following groups: (A) Mono-species biofilms formed by C. albicans, co-cultivated C. albicans plus P. brasiliensis biofilms or dual-species biofilms formed by the addition of P. brasiliensis inoculum to preformed 12 h C. albicans biofilms (*p < 0.001). (B) Mono-species biofilms formed by P. brasiliensis, co-cultivated C. albicans plus P. brasiliensis biofilms or dual-species biofilms formed by the addition of P. brasiliensis inoculum to preformed 12 h C. albicans biofilms. Statistical significances were calculated by using analysis of variance (ANOVA) followed by Bonferroni test.