Table 1.
Gene name, fold change and p-value of differentially expressed genes between PP and DP following PDL in Ptf1a-Cre(+/ki); K-ras LSLG12Vgeo(+/ki mice.
| Gene symbol | Gene name | logFoldChange | adj.P.Val |
|---|---|---|---|
| Cel | Carboxyl ester lipase | − 3.63 | 0.0002 |
| Sycn | Syncollin | − 3.42 | 0.0012 |
| Klk1 | Kallikrein 1 | − 3.01 | 0.0014 |
| Pnliprp1 | Pancreatic lipase related protein 1 | − 3.04 | 0.0014 |
| Nupr1 | Nuclear protein transcription regulator 1 | − 2.82 | 0.0016 |
| Gm5409 | Predicted pseudogene 5409 | − 2.42 | 0.0017 |
| Try5 | Trypsin 5 | − 2.92 | 0.0017 |
| 2210010C04Rik | RIKEN cDNA 2210010C04 gene | − 2.14 | 0.0019 |
| Prss1 | Protease, serine 1 (trypsin 1) | − 2.74 | 0.0020 |
| Prss2 | Protease, serine 2 | − 2.93 | 0.0020 |
| Rnase1 | Ribonuclease, RNase A family, 1 (pancreatic) | − 4.17 | 0.0024 |
| Zg16 | Zymogen granule protein 16 | − 2.23 | 0.0024 |
| Cpb1 | Carboxypeptidase B1 (tissue) | − 2.71 | 0.0025 |
| Try10 | Trypsin 10 | − 2.42 | 0.0025 |
| Gm5771 | Predicted gene 5771 | − 2.30 | 0.0026 |
| Cpa1 | Carboxypeptidase A1, pancreatic | − 2.51 | 0.0026 |
| Ctrl | Chymotrypsin-like | − 2.55 | 0.0030 |
| Cela2a | Chymotrypsin-like elastase family, member 2A | − 2.39 | 0.0030 |
| Cela1 | Chymotrypsin-like elastase family, member 1 | − 2.07 | 0.0049 |
| Gp2 | Glycoprotein 2 (zymogen granule membrane) | − 2.29 | 0.0068 |
| Clps | Colipase, pancreatic | − 3.26 | 0.0070 |
| Pnlip | Pancreatic lipase | − 1.70 | 0.0070 |
| Try4 | Trypsin 4 | − 2.58 | 0.0070 |
| Cpa2 | Carboxypeptidase A2, pancreatic | − 2.91 | 0.0073 |
| Pnliprp2 | Pancreatic lipase-related protein 2 | − 2.24 | 0.0077 |
| Ctrb1 | Chymotrypsinogen B1 | − 3.45 | 0.0089 |
| Amy2a1 | Amylase 2a1 | − 3.10 | 0.0095 |
| Cela3b | Chymotrypsin-like elastase family, member 3B | − 2.23 | 0.0095 |
| Cela3a | Chymotrypsin-like elastase family, member 3A | − 1.89 | 0.0152 |
| Mt1 | Metallothionein 1 | − 2.05 | 0.0162 |
| Nhsl1 | NHS-like 1 | 1.55 | 0.0181 |
| Dmbt1 | Deleted in malignant brain tumors 1 | − 1.55 | 0.0189 |
| Ggt1 | Gamma-glutamyltransferase 1 | − 2.10 | 0.0260 |
| Reg1 | Regenerating islet-derived 1 | − 2.39 | 0.0283 |
| Gm10334 | Predicted gene 10334 | − 1.50 | 0.0304 |
| Tff2 | Trefoil factor 2 (spasmolytic protein 1) | − 2.96 | 0.0429 |
| Srpr | Signal recognition particle receptor (docking protein) | − 1.31 | 0.0488 |
| Zdhhc16 | Zinc finger, DHHC domain containing 16 | 2.04 | 0.0491 |
38 genes were selected with a p-value < 0.05.