Skip to main content
. 2020 Oct 27;10:18400. doi: 10.1038/s41598-020-75376-z

Figure 1.

Figure 1

PTX3 protein expression and co-localization with PSA in first PBx of patients subsequently developing prostate cancer (group A) or not (group B). PTX3 (green; A and E) and PSA (red; B and F) protein expression were evaluated in the first PBx by double label immunofluorescence and confocal microscopy as detailed in Materials and Methods. TO-PRO-3 was used to stain nuclei (blue; C and G). Merged images (D and H) demonstrate the co-localization of the two protein signals (yellow). Mean fluorescence intensity (MFI) quantification confirmed a statistically significant higher PTX3 expression in group A compared to group B (I, J). Bar length = 50 µ.